Syntheses of Medicaments derived from Resorcinol. VII

Syntheses of C2-symmetric vicinal diamines derived from tartaric acid

C2-symmetric vicinal diamines 3b–f, derived from L-tartaric acid, with increasingly bulky terminal ether functionalities were prepared using two distinct sequences. Diamines 3b,c were obtained from the corresponding vicinal diols 4b,c, while diamines 3d–f were generated from dihydroxydiazide 7 via deprotection–reprotection strategies. © 1999 Elsevier Science Ltd. All rights reserved.

UV promoted phenanthridine syntheses from oxime carbonate derived iminyl radicals.

Oxime carbonates were found to be excellent precursors for the clean and direct generation of iminyl radicals under UV irradiation. Suitably functionalised iminyls underwent cyclisations yielding various phenanthridines and also substituted quinolines and isoquinolines. EPR and X-ray analyses of oxime carbonates provided insight into the mechanism.

Derived Algebraic Geometry VII: Spectral Schemes

Potential fluoride toxicity from oral medicaments: A review

The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than the recommended limit leads to toxicity and adverse effects. In order to update our understanding ...

Derived Algebraic Geometry VII: Spectral Schemes